RPS27AP18

Across TCGA pan-cancer cohorts, RPS27AP18 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated RPS27AP18 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher RPS27AP18 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RPS27AP18 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LAML show a favorable association.

KICH, MESO, and ACC are the cancer types where RPS27AP18 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.081	0.904	<.001	90	view →
MESO	OS	Tertile	All	0.339	0.580	.009	90	view →
ACC	OS	Tertile	II,III,IV	0.703	0.911	<.001	61	view →
KIRC	OS	Tertile	All	0.500	0.673	<.001	58	view →
PAAD	DFS	Tertile	All	0.255	0.498	.001	51	view →
LUSC	OS	Tertile	IV	0.001	0.673	.014	36	view →
TGCT	DFS	Tertile	II,III,IV	0.015	0.919	<.001	36	view →
LUAD	DFS	Tertile	All	0.539	0.301	.015	27	view →
LIHC	DFS	Tertile	III,IV	0.159	0.375	.019	18	view →
LGG	OS	Tertile	All	0.827	0.905	.017	12	view →
ESCA	DFS	Tertile	All	0.415	0.573	.017	11	view →
THCA	DFS	Tertile	III,IV	0.506	0.783	.025	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

RPS27AP18–KICH (DFS)

Open the KICH breakdown →