RPS27AP18

Across TCGA pan-cancer cohorts, RPS27AP18 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RPS27AP18’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where RPS27AP18 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPS27AP18 is over-expressed in tumor.

BRCA, LUSC, and LUAD are the cancer types where RPS27AP18 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS27AP18 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	II,III,IV	+0.049	<.001	4	view →
LUSC	All	All	+0.053	.004	2	view →
LUAD	All	All	+0.044	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

RPS27AP18–BRCA

Open the BRCA breakdown →