RPS26

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RPS26 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated RPS26 data layer compared with 26 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher RPS26 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated RPS26 expression acts as an unfavorable survival marker, although some lineages such as LSCC and LUAD show a favorable association.

CCRCC, GBM, and PDAC are the cancer types where RPS26 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CCRCCOSQuartileAll0.6820.991.00151view →
GBMDFSQuartileAll0.2090.406.01010view →
PDACDFSMedianIV0.2140.785.0069view →
LSCCDFSQuartileII,III,IV1.0000.386.0245view →
LUADDFSTertileAll0.9560.769.0441view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration