RPS23P8

Across TCGA pan-cancer cohorts, RPS23P8 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of RPS23P8’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPS23P8 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPS23P8 is over-expressed in tumor, although a few such as KICH and BRCA show the opposite, repressed pattern.

KIRC, COAD, and LIHC are the cancer types where RPS23P8 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS23P8 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	II,III,IV	+0.926	<.001	12	view →
COAD	Female	II,III,IV	+1.857	<.001	11	view →
LIHC	Female	II,III,IV	+0.988	<.001	6	view →
KIRP	All	III,IV	+0.551	.023	4	view →
CHOL	All	All	+1.646	<.001	3	view →
KICH	Female	All	−0.702	.004	3	view →
READ	Female	All	+0.948	.008	2	view →
THCA	Female	II,III,IV	+0.586	.011	2	view →
BRCA	All	All	−0.255	.019	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

RPS23P8–KIRC

Open the KIRC breakdown →