Across TCGA pan-cancer cohorts, RPS23P6 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RPS23P6’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where RPS23P6 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPS23P6 is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.
STAD, CHOL, and KICH are the cancer types where RPS23P6 tumor–normal differential expression is most reproducible.