RPS23P1

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RPS23P1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated RPS23P1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RPS23P1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RPS23P1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and COAD show a favorable association.

HNSC, STAD, and COAD are the cancer types where RPS23P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCDFSTertileIII,IV0.6810.489.00166view →
STADOSQuartileAll0.4830.671.00242view →
COADOSMedianAll0.8960.731.00128view →
ESCADFSMedianAll0.2580.457.00324view →
UCSOSTertileIV0.8980.360.03624view →
ACCDFSMedianII,III,IV0.3910.748.00419view →
BRCADFSMedianIII,IV0.9250.827.00316view →
KICHDFSTertileAll0.7170.953.00816view →
PRADDFSQuartileAll0.9610.842.00714view →
UVMOSTertileAll0.8320.487.00612view →
CESCDFSMedianII,III,IV0.7970.601.00912view →
THYMOSMedianII,III,IV0.9740.662.0058view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

RPS23P1–HNSC (DFS)

Kaplan–Meier survival curve for RPS23P1 RNA-high vs -low samples in HNSC.

Open the HNSC breakdown →

Exploration