RPS23P1

Across TCGA pan-cancer cohorts, RPS23P1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of RPS23P1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where RPS23P1 RNA is repressed in tumor relative to normal tissue. In most cancer types RPS23P1 is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

THCA, LUSC, and KIRC are the cancer types where RPS23P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS23P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Female	II,III,IV	−1.435	<.001	11	view →
LUSC	Male	II,III,IV	+0.434	<.001	7	view →
KIRC	All	All	−0.176	<.001	7	view →
BRCA	All	All	−0.658	<.001	6	view →
KICH	Female	All	−0.522	<.001	4	view →
UCEC	All	All	−0.520	.013	4	view →
COAD	All	II,III,IV	+0.325	.030	3	view →
LIHC	All	All	+0.195	<.001	3	view →
PRAD	All	All	−0.236	.006	2	view →
LUAD	All	All	+0.160	.020	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

RPS23P1–THCA

Open the THCA breakdown →