RPS18P6

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RPS18P6 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible RPS18P6-associated genes across cancer lineages are RNU6-379P, MT-TD, and VPS13A-AS1. Each is linked with RPS18P6 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPS18P6-to-partner and partner-to-RPS18P6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-379P grouped by RPS18P6-low versus RPS18P6-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS18P6→partner) and Y-score (partner→RPS18P6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMRNU6-379P →+0.462+4.215<.001.00931
SKCMMT-TD →+0.318+4.771<.001.00631
SKCMVPS13A-AS1 →+0.177+4.241<.001.00831
LUADLINC00709 →+0.079+7.930<.001.00831
SKCMRNA5SP143 →+0.213+5.199<.001.00331
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

RNU6-379P by RPS18P6 expression — SKCM

Box plot of RNU6-379P in RPS18P6-low vs RPS18P6-high samples in SKCM.

Explore this box plot interactively →

Exploration