RPS17

Across TCGA patient cohorts, RPS17 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible RPS17-associated genes across cancer lineages are RNU6-1228P, RARRES2P10, and GARS1P1. Each is linked with RPS17 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPS17-to-partner and partner-to-RPS17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1228P grouped by RPS17-low versus RPS17-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS17→partner) and Y-score (partner→RPS17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-1228P →	+0.327	+5.464	<.001	.001	3	2
BLCA	RARRES2P10 →	+0.233	+5.411	.009	.005	3	1
BLCA	GARS1P1 →	+0.128	+5.588	<.001	.004	3	1
BLCA	MIR4305 →	+0.396	+5.177	.001	.007	3	1
BLCA	PISRT1 →	+0.135	+5.899	<.001	.002	3	1
UCEC	MIR5008 →	+0.461	+4.109	.003	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

RNU6-1228P by RPS17 expression — UCEC

Explore this box plot interactively →