Q-omics provides the consensus-scored RPS15AP28 profile across patient tissues and cancer cell-line models. RPS15AP28 expression is associated with patient survival in 17 of 34 cancer types, with the highest sampling consensus in SKCM. Among the 18 cancer types available for tumor–normal comparison, RPS15AP28 is differentially expressed in 5, with the highest sampling consensus in COAD. Additionally, RPS15AP28 RNA expression shows 5,761 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight SKCM, COAD, and STAD as cancer lineages where RPS15AP28 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RPS15AP28 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RPS15AP28 survival associations across molecular data types. RPS15AP28 RNA expression shows survival associations in the most cancer types (17). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RPS15AP28 RNA expression–survival associations across cancer types. High RPS15AP28 expression shows unfavorable associations in BRCA, KIRP, STAD and MESO, but favorable associations in SKCM and CESC. The SKCM Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify SKCM as the clearest survival context for RPS15AP28 RNA expression.
This table summarizes RPS15AP28 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for RPS15AP28. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RPS15AP28 shows lower tumor expression in THCA and higher tumor expression in COAD, HNSC, LUAD and KIRC. The COAD box plot shows higher RPS15AP28 RNA expression in tumor versus normal tissue (log2 FC = +0.320, t-test p = .009).
This table shows molecular features associated with RPS15AP28 in patient tissues and cancer cell lines. In patient samples, RPS15AP28 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
