RPS12P3

Across TCGA pan-cancer cohorts, RPS12P3 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of RPS12P3’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RPS12P3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPS12P3 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

HNSC, KICH, and BLCA are the cancer types where RPS12P3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS12P3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	All	+0.919	<.001	10	view →
KICH	Female	All	−1.004	<.001	7	view →
BLCA	All	III,IV	+0.942	.006	7	view →
BRCA	All	II,III,IV	+0.601	<.001	6	view →
COAD	Female	All	+0.355	.032	3	view →
STAD	All	II,III,IV	+0.452	.038	1	view →
THCA	All	All	−0.255	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

RPS12P3–HNSC

Open the HNSC breakdown →