RPS12P27

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RPS12P27 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated RPS12P27 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher RPS12P27 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RPS12P27 expression acts as an unfavorable survival marker, although some lineages such as THCA and HNSC show a favorable association.

THCA, HNSC, and LUSC are the cancer types where RPS12P27 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
THCADFSMedianIV1.0000.525.00249view →
HNSCDFSTertileAll0.7670.656.01127view →
LUSCDFSMedianII,III,IV0.4470.253.00326view →
ACCOSTertileAll0.6760.952.00524view →
DLBCDFSTertileII,III,IV1.0000.555.01017view →
BLCADFSTertileAll0.3830.554.01910view →
CHOLDFSQuartileII,III,IV0.1640.523.0408view →
READDFSMedianIV0.9360.179.0108view →
LAMLDFSTertileAll0.6790.489.0358view →
CESCOSTertileII,III,IV0.8280.625.0256view →
LGGOSQuartileAll0.9370.847.0263view →
UVMDFSQuartileII,III,IV0.8280.582.0432view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

RPS12P27–THCA (DFS)

Kaplan–Meier survival curve for RPS12P27 RNA-high vs -low samples in THCA.

Open the THCA breakdown →

Exploration