Q-omics provides the consensus-scored RPS12P27 profile across patient tissues and cancer cell-line models. RPS12P27 expression is associated with patient survival in 16 of 34 cancer types, with the highest sampling consensus in THCA. Among the 18 cancer types available for tumor–normal comparison, RPS12P27 is differentially expressed in 10, with the highest sampling consensus in COAD. Additionally, RPS12P27 RNA expression shows 9,121 significant gene co-expression associations, with the highest sampling consensus in LAML. Together, these results highlight THCA, COAD, and LAML as cancer lineages where RPS12P27 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RPS12P27 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RPS12P27 survival associations across molecular data types. RPS12P27 RNA expression shows survival associations in the most cancer types (16). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RPS12P27 RNA expression–survival associations across cancer types. High RPS12P27 expression shows unfavorable associations in ACC and BLCA, but favorable associations in THCA, HNSC, LUSC and DLBC. The THCA Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .002). Together, the overview and detailed table identify THCA as the clearest survival context for RPS12P27 RNA expression.
This table summarizes RPS12P27 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for RPS12P27. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RPS12P27 shows lower tumor expression in LUAD, THCA and BRCA and higher tumor expression in COAD, UCEC and KIRC. The COAD box plot shows higher RPS12P27 RNA expression in tumor versus normal tissue (log2 FC = +0.745, t-test p < 0.001).
This table shows molecular features associated with RPS12P27 in patient tissues and cancer cell lines. In patient samples, RPS12P27 shows the broadest associations at the RNA and protein expression levels, with LAML recurring as the lineage with the largest associated feature set.
