RPS12P23

Across TCGA pan-cancer cohorts, RPS12P23 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated RPS12P23 data layer compared with 1 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher RPS12P23 RNA is associated with better overall survival. In most high-consensus cancer types, elevated RPS12P23 expression acts as an unfavorable survival marker, although some lineages such as LUSC and BLCA show a favorable association.

LUSC, KICH, and OV are the cancer types where RPS12P23 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Median	All	0.825	0.698	<.001	63	view →
KICH	OS	Tertile	II,III,IV	0.779	1.000	.004	44	view →
OV	OS	Tertile	All	0.641	0.719	.020	34	view →
BLCA	DFS	Quartile	All	0.682	0.538	.004	33	view →
UCEC	OS	Median	All	0.531	0.792	.001	32	view →
CHOL	DFS	Tertile	II,III,IV	0.111	0.503	.029	30	view →
LIHC	DFS	Median	II,III,IV	0.204	0.458	.002	28	view →
MESO	OS	Median	II,III,IV	0.449	0.677	.002	25	view →
PAAD	OS	Quartile	All	0.401	0.731	<.001	19	view →
READ	DFS	Median	IV	0.936	0.179	.010	8	view →
PCPG	DFS	Median	All	1.000	0.704	.004	8	view →
LAML	DFS	Quartile	All	0.529	0.240	.018	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

RPS12P23–LUSC (OS)

Open the LUSC breakdown →