RPS12P23

Across TCGA pan-cancer cohorts, RPS12P23 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of RPS12P23’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where RPS12P23 RNA is repressed in tumor relative to normal tissue. In most cancer types RPS12P23 is over-expressed in tumor, although a few such as UCEC show the opposite, repressed pattern.

UCEC, COAD, and LIHC are the cancer types where RPS12P23 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS12P23 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	IV	−0.880	.010	4	view →
COAD	All	II,III,IV	+0.359	.006	4	view →
LIHC	Female	All	+0.145	.009	2	view →
STAD	All	IV	+0.543	.032	1	view →
CHOL	Female	All	+0.243	.045	1	view →
THCA	Female	III,IV	+0.180	.023	1	view →
KIRC	All	All	+0.084	.010	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

RPS12P23–UCEC

Open the UCEC breakdown →