ribosomal protein S12 pseudogene 2Genealiases: RPS12_9_1071 · bA40F6.3
Q-omics provides the consensus-scored RPS12P2 profile across patient tissues and cancer cell-line models. RPS12P2 expression is associated with patient survival in 14 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, RPS12P2 is differentially expressed in 6, with the highest sampling consensus in CHOL. Additionally, RPS12P2 RNA expression shows 8,181 significant gene co-expression associations, with the highest sampling consensus in KIRP. Together, these results highlight KIRC, CHOL, and KIRP as cancer lineages where RPS12P2 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RPS12P2 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RPS12P2 survival associations across molecular data types. RPS12P2 RNA expression shows survival associations in the most cancer types (14). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RPS12P2 RNA expression–survival associations across cancer types. High RPS12P2 expression shows unfavorable associations in KIRC, TGCT, LUAD, BRCA and OV, but favorable associations in READ. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .006). Together, the overview and detailed table identify KIRC as the clearest survival context for RPS12P2 RNA expression.
This table summarizes RPS12P2 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 6. The strongest signals are observed in CHOL for RNA.
This table ranks reproducible tumor–normal expression differences for RPS12P2. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RPS12P2 shows higher tumor expression in CHOL, LUAD, COAD, STAD, KIRP and HNSC. The CHOL box plot shows higher RPS12P2 RNA expression in tumor versus normal tissue (log2 FC = +0.641, t-test p = .002).
This table shows molecular features associated with RPS12P2 in patient tissues and cancer cell lines. In patient samples, RPS12P2 shows the broadest associations at the RNA and protein expression levels, with KIRP recurring as the lineage with the largest associated feature set.
