RPRD1B

Across TCGA pan-cancer cohorts, RPRD1B mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated RPRD1B data layer compared with 27 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher RPRD1B mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RPRD1B expression acts as an unfavorable survival marker, although some lineages such as COAD and GBM show a favorable association.

COAD, GBM, and CCRCC are the cancer types where RPRD1B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Quartile	All	1.000	0.817	.039	24	view →
GBM	OS	Tertile	All	0.527	0.284	.027	6	view →
CCRCC	DFS	Median	III,IV	0.811	0.550	.013	3	view →
UCEC	OS	Median	All	0.912	0.985	.033	2	view →
LUAD	OS	Median	II,III,IV	0.874	0.473	.043	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RPRD1B–COAD (DFS)

Open the COAD breakdown →