RPRD1B

Across TCGA patient cohorts, RPRD1B mutation is significantly associated with the RNA expression of many other genes, with 1,088 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPRD1B-associated genes across cancer lineages are RNU1-80P, MIR4662B, and RNA5SP412. Each is linked with RPRD1B in more than 1 cancer types. Because this analysis shows association rather than direction, both RPRD1B-to-partner and partner-to-RPRD1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-80P grouped by RPRD1B-low versus RPRD1B-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPRD1B→partner) and Y-score (partner→RPRD1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU1-80P →	+0.217	+5.378	.001	.006	3	2
LUSC	MIR4662B →	+0.656	+5.093	<.001	.008	3	2
UCEC	RNA5SP412 →	+0.514	+1.867	<.001	.007	3	2
BRCA	RN7SL585P →	+0.451	+6.064	<.001	.002	3	1
BRCA	MIR6885 →	+0.811	+5.070	<.001	.008	3	1
UCEC	C9orf50 →	-0.506	-3.700	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,088 associations by consensus.

RNU1-80P by RPRD1B expression — BRCA

Explore this box plot interactively →