RPRD1B

Across TCGA cell cohorts, RPRD1B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,910 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible RPRD1B-associated GO terms across cancer lineages are Promoter clearance during DNA-templated transcription, RNA polymerase II promoter clearance, and Regulation of double-strand break repair via homologous recombination. Each is linked with RPRD1B in more than 19 cancer types. Because this analysis shows association rather than direction, both RPRD1B-to-partner and partner-to-RPRD1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Promoter clearance during DNA-templated transcription grouped by RPRD1B-low versus RPRD1B-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPRD1B→partner) and Y-score (partner→RPRD1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Promoter clearance during DNA-templated transcription →	+0.169	+0.828	<.001	.001	3	20
URINARY_TRACT	RNA polymerase II promoter clearance →	+0.169	+0.828	<.001	.001	3	20
SOFT_TISSUE	Regulation of double-strand break repair via homologous recombination →	+0.072	+0.541	<.001	<.001	3	17
LARGE_INTESTINE	Regulation of mRNA processing →	+0.085	+0.901	<.001	<.001	3	15
LARGE_INTESTINE	Heterochromatin formation →	+0.064	+0.855	<.001	<.001	3	15
BONE	Nucleic acid transport →	+0.109	+0.481	<.001	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,910 associations by consensus.

Promoter clearance during DNA-templated transcription by RPRD1B expression — URINARY_TRACT

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