RPRD1A

Across TCGA patient cohorts, RPRD1A mutation is significantly associated with the RNA expression of many other genes, with 1,169 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPRD1A-associated genes across cancer lineages are STMN1P2, OR8A2P, and TSPY4. Each is linked with RPRD1A in more than 1 cancer types. Because this analysis shows association rather than direction, both RPRD1A-to-partner and partner-to-RPRD1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, STMN1P2 grouped by RPRD1A-low versus RPRD1A-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPRD1A→partner) and Y-score (partner→RPRD1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	STMN1P2 →	+0.104	+5.241	.006	.007	3	2
HNSC	OR8A2P →	+0.212	+5.368	<.001	.005	3	2
SKCM	TSPY4 →	+0.015	+4.993	.005	.002	3	2
BLCA	RNU7-107P →	+0.436	+4.433	<.001	.007	3	2
THCA	RN7SKP20 →	+0.119	+7.962	<.001	.007	3	1
THCA	RN7SKP6 →	+0.119	+7.962	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,169 associations by consensus.

STMN1P2 by RPRD1A expression — HNSC

Explore this box plot interactively →