RPP40

Across TCGA patient cohorts, RPP40 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,162 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RPP40-associated proteins across cancer lineages are XPO5, RIOK1, and ABCF1. Each is linked with RPP40 in more than 9 cancer types. Because this analysis shows association rather than direction, both RPP40-to-partner and partner-to-RPP40 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPP40 versus XPO5 in LSCC, with a Pearson correlation of 0.71.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RPP40→partner) and Y-score (partner→RPP40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	XPO5 →	+0.743	+0.941	<.001	<.001	3	10
COAD	RIOK1 →	+0.885	+0.847	.007	.004	3	9
OV	ABCF1 →	+0.264	+0.651	.004	.001	3	8
OV	WDR75 →	+0.407	+0.629	<.001	.002	3	8
LSCC	GMPS →	+0.488	+0.769	<.001	<.001	3	8
LSCC	RRP36_S73 →	+0.940	+0.719	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,162 associations by consensus.

RPP40 vs XPO5 — LSCC

Explore this scatter interactively →