RPP38

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RPP38 protein abundance is significantly associated with the RNA expression of many other genes, with 13,633 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RPP38-associated genes across cancer lineages are CCNB1IP1, EIF3E, and DCAF13. Each is linked with RPP38 in more than 4 cancer types. Because this analysis shows association rather than direction, both RPP38-to-partner and partner-to-RPP38 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPP38 versus CCNB1IP1 in BRCA, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPP38→partner) and Y-score (partner→RPP38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCACCNB1IP1 →+0.748+0.252<.001<.00135
OVEIF3E →+1.017+0.469<.001<.00135
BRCADCAF13 →+0.607+0.318<.001<.00135
LSCCC19orf48 →+0.858+0.207<.001<.00135
LUADPABPC1 →+0.810+0.236<.001<.00135
LSCCXPO5 →+0.765+0.235<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,633 associations by consensus.

RPP38 vs CCNB1IP1 — BRCA

Per-sample scatter of RPP38 vs CCNB1IP1 in BRCA (Pearson r = 0.33).

Explore this scatter interactively →

Exploration