RPP38

Across TCGA cell cohorts, RPP38 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,179 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RPP38-associated GO terms across cancer lineages are Mitochondrial RNA 3'-end processing, 'de novo' cotranslational protein folding, and Positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Each is linked with RPP38 in more than 13 cancer types. Because this analysis shows association rather than direction, both RPP38-to-partner and partner-to-RPP38 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial RNA 3'-end processing grouped by RPP38-low versus RPP38-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPP38→partner) and Y-score (partner→RPP38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Mitochondrial RNA 3'-end processing →	+0.114	+0.779	<.001	<.001	3	14
LUNG_NSCLC_LUSC	'de novo' cotranslational protein folding →	+0.129	+0.718	.009	<.001	2	14
BLOOD_Myeloma	Positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.146	+0.897	<.001	.001	3	13
BONE	tRNA 5'-leader removal →	+0.136	+0.462	<.001	.007	3	11
LIVER	Pentose catabolic process →	+0.140	+0.621	<.001	<.001	3	11
BONE	tRNA 5'-end processing →	+0.140	+0.453	<.001	.004	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,179 associations by consensus.

Mitochondrial RNA 3'-end processing by RPP38 expression — BLOOD_Myeloma

Explore this box plot interactively →