RPP25

Across TCGA cell cohorts, RPP25 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,822 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RPP25-associated GO terms across cancer lineages are Body fluid secretion, tRNA 5'-leader removal, and Mitochondrial ribosome assembly. Each is linked with RPP25 in more than 7 cancer types. Because this analysis shows association rather than direction, both RPP25-to-partner and partner-to-RPP25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Body fluid secretion grouped by RPP25-low versus RPP25-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPP25→partner) and Y-score (partner→RPP25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Body fluid secretion →	+0.155	+1.670	<.001	<.001	3	8
LUNG_SCLC	tRNA 5'-leader removal →	+0.118	+1.375	<.001	<.001	3	7
BONE	Mitochondrial ribosome assembly →	+0.089	+2.440	<.001	<.001	3	7
BLOOD_Leukemia	GDP-L-fucose metabolic process →	+0.072	+1.642	<.001	<.001	3	7
LUNG_NSCLC_LUAD	Vasculogenesis →	-0.059	-0.999	.001	<.001	2	7
URINARY_TRACT	Rostrocaudal neural tube patterning →	+0.165	+2.366	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,822 associations by consensus.

Body fluid secretion by RPP25 expression — BONE

Explore this box plot interactively →