RPP21

Across TCGA patient cohorts, RPP21 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,027 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RPP21-associated proteins across cancer lineages are ZNF318, SF3B3, and API5. Each is linked with RPP21 in more than 5 cancer types. Because this analysis shows association rather than direction, both RPP21-to-partner and partner-to-RPP21 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPP21 versus ZNF318 in LSCC, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RPP21→partner) and Y-score (partner→RPP21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ZNF318 →	+0.349	+0.398	<.001	<.001	3	6
BRCA	SF3B3 →	+0.206	+0.471	<.001	<.001	3	6
BRCA	API5 →	+0.204	+0.578	.004	<.001	3	6
GBM	STAG2 →	+0.246	+0.225	.001	<.001	3	6
GBM	PNN →	+0.338	+0.250	<.001	<.001	3	5
BRCA	PRPF4B →	+0.255	+0.439	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,027 associations by consensus.

RPP21 vs ZNF318 — LSCC

Explore this scatter interactively →