RPP21

Across TCGA patient cohorts, RPP21 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible RPP21-associated genes across cancer lineages are MIR5702 and RNU6-1148P. Each is linked with RPP21 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPP21-to-partner and partner-to-RPP21 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR5702 grouped by RPP21-low versus RPP21-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPP21→partner) and Y-score (partner→RPP21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR5702 →	+0.333	+7.816	<.001	.008	3	1
SKCM	RNU6-1148P →	+0.278	+7.816	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

MIR5702 by RPP21 expression — SKCM

Explore this box plot interactively →