RPP21

Across TCGA cell cohorts, RPP21 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,807 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RPP21-associated GO terms across cancer lineages are Protein peptidyl-prolyl isomerization, Proteasome core complex assembly, and [2Fe-2S] cluster assembly. Each is linked with RPP21 in more than 12 cancer types. Because this analysis shows association rather than direction, both RPP21-to-partner and partner-to-RPP21 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein peptidyl-prolyl isomerization grouped by RPP21-low versus RPP21-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPP21→partner) and Y-score (partner→RPP21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Protein peptidyl-prolyl isomerization →	+0.113	+0.833	<.001	.001	3	13
PANCREAS	Proteasome core complex assembly →	+0.095	+0.584	.002	.001	3	9
PANCREAS	[2Fe-2S] cluster assembly →	+0.102	+0.677	<.001	<.001	3	9
BLOOD_Leukemia	Metanephric loop of Henle development →	-0.213	-0.660	<.001	<.001	3	8
LUNG_NSCLC_LUAD	L-serine transport →	-0.112	-0.445	.001	.004	3	8
LARGE_INTESTINE	Regulation of cell size →	-0.056	-0.415	<.001	.008	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,807 associations by consensus.

Protein peptidyl-prolyl isomerization by RPP21 expression — BLOOD_Myeloma

Explore this box plot interactively →