RPP14

Across TCGA patient cohorts, RPP14 mutation is significantly associated with the RNA expression of many other genes, with 381 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPP14-associated genes across cancer lineages are RNU6-391P, LINC00529, and LINC01784. Each is linked with RPP14 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPP14-to-partner and partner-to-RPP14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-391P grouped by RPP14-low versus RPP14-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPP14→partner) and Y-score (partner→RPP14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-391P →	+0.281	+3.612	<.001	.003	3	2
UCEC	LINC00529 →	+0.113	+3.356	.007	.005	3	2
SKCM	LINC01784 →	+0.094	+7.816	<.001	.008	3	2
SKCM	ACTR3BP6 →	+0.029	+7.816	<.001	.008	3	1
UCEC	NOCT →	+1.113	+3.332	<.001	.005	3	1
UCEC	C16orf87 →	+0.744	+3.364	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 381 associations by consensus.

RNU6-391P by RPP14 expression — UCEC

Explore this box plot interactively →