RPLP1

Across TCGA pan-cancer cohorts, RPLP1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated RPLP1 data layer compared with 26 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher RPLP1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated RPLP1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and PDAC show a favorable association.

CCRCC, LUAD, and PDAC are the cancer types where RPLP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Quartile	All	0.640	1.000	<.001	59	view →
LUAD	DFS	Median	All	0.983	0.846	.001	12	view →
PDAC	DFS	Tertile	II,III,IV	0.916	0.753	.013	7	view →
HNSC	OS	Tertile	II,III,IV	0.945	1.000	.043	2	view →
GBM	DFS	Tertile	All	0.654	0.854	.027	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RPLP1–CCRCC (OS)

Open the CCRCC breakdown →