RPL7AP25

Across TCGA pan-cancer cohorts, RPL7AP25 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated RPL7AP25 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher RPL7AP25 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPL7AP25 expression acts as an unfavorable survival marker, although some lineages such as THCA and LGG show a favorable association.

UCS, STAD, and ESCA are the cancer types where RPL7AP25 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Tertile	All	0.282	0.633	<.001	144	view →
STAD	DFS	Quartile	All	0.182	0.586	<.001	51	view →
ESCA	DFS	Quartile	II,III,IV	0.253	0.467	.006	39	view →
BRCA	DFS	Tertile	All	0.570	1.000	.033	36	view →
KICH	DFS	Tertile	III,IV	0.025	0.773	<.001	36	view →
ACC	OS	Tertile	IV	0.327	0.633	.045	18	view →
GBM	DFS	Tertile	All	0.181	0.281	.007	12	view →
PRAD	OS	Tertile	All	0.972	0.998	.003	12	view →
THCA	DFS	Tertile	All	0.930	0.807	.049	3	view →
THYM	DFS	Tertile	II,III,IV	0.666	0.897	.042	3	view →
LGG	OS	Median	All	0.612	0.429	.017	2	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

RPL7AP25–UCS (OS)

Open the UCS breakdown →