RPL7A

Across TCGA patient cohorts, RPL7A mutation is significantly associated with the RNA expression of many other genes, with 461 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL7A-associated genes across cancer lineages are RNA5SP407, RNU6-1228P, and NFYBP1. Each is linked with RPL7A in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL7A-to-partner and partner-to-RPL7A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP407 grouped by RPL7A-low versus RPL7A-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL7A→partner) and Y-score (partner→RPL7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNA5SP407 →	+0.238	+7.954	<.001	.008	3	2
UCEC	RNU6-1228P →	+0.179	+3.879	.004	.009	3	2
UCEC	NFYBP1 →	+0.341	+2.572	<.001	.006	3	2
LUSC	MTCO3P9 →	+0.069	+5.792	<.001	.003	3	2
HNSC	MIR544A →	+0.318	+7.954	<.001	.008	3	1
BLCA	RNU6-586P →	+0.332	+7.640	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 461 associations by consensus.

RNA5SP407 by RPL7A expression — HNSC

Explore this box plot interactively →