RPL7

Across TCGA patient cohorts, RPL7 mutation is significantly associated with the RNA expression of many other genes, with 169 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible RPL7-associated genes across cancer lineages are RAB28P2, RNA5SP57, and HAUS1P3. Each is linked with RPL7 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL7-to-partner and partner-to-RPL7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RAB28P2 grouped by RPL7-low versus RPL7-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL7→partner) and Y-score (partner→RPL7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RAB28P2 →	+0.126	+4.624	<.001	.005	3	2
COAD	RNA5SP57 →	+0.940	+6.721	<.001	<.001	3	2
SKCM	HAUS1P3 →	+0.040	+4.469	<.001	.006	3	2
SKCM	MIR2681 →	+0.233	+6.228	<.001	<.001	3	2
SKCM	RNU6-1246P →	+0.195	+5.810	<.001	<.001	3	2
BRCA	RNA5SP121 →	+0.309	+9.057	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 169 associations by consensus.

RAB28P2 by RPL7 expression — SKCM

Explore this box plot interactively →