RPL6P27

Across TCGA pan-cancer cohorts, RPL6P27 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated RPL6P27 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher RPL6P27 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RPL6P27 expression acts as an unfavorable survival marker, although some lineages such as BLCA and LGG show a favorable association.

ACC, LUAD, and LIHC are the cancer types where RPL6P27 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.259	0.629	<.001	111	view →
LUAD	DFS	Median	III,IV	0.264	0.657	<.001	75	view →
LIHC	OS	Quartile	All	0.553	0.758	.001	67	view →
BLCA	DFS	Quartile	II,III,IV	0.613	0.396	<.001	60	view →
BRCA	DFS	Median	II,III,IV	0.853	0.921	<.001	32	view →
LGG	DFS	Tertile	All	0.813	0.663	<.001	30	view →
KIRC	DFS	Tertile	IV	0.634	0.339	.013	30	view →
THCA	DFS	Median	All	0.888	0.775	.005	29	view →
UCEC	DFS	Tertile	All	0.464	0.710	.002	26	view →
MESO	DFS	Median	All	0.626	0.269	.009	21	view →
UVM	DFS	Median	III,IV	0.471	0.818	.008	20	view →
SARC	OS	Tertile	All	0.676	0.854	.001	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

RPL6P27–ACC (DFS)

Open the ACC breakdown →