RPL5P6

Across TCGA pan-cancer cohorts, RPL5P6 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated RPL5P6 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RPL5P6 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPL5P6 expression acts as an unfavorable survival marker, although some lineages such as CESC and KIRP show a favorable association.

UCEC, ACC, and LUAD are the cancer types where RPL5P6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Quartile	II,III,IV	0.278	0.756	.002	46	view →
ACC	OS	Median	All	0.430	0.768	.002	44	view →
LUAD	OS	Median	All	0.724	0.843	.006	20	view →
CESC	DFS	Quartile	III,IV	0.925	0.246	.003	18	view →
LUSC	OS	Quartile	II,III,IV	0.367	0.693	.010	16	view →
KIRP	DFS	Tertile	All	0.939	0.796	.003	15	view →
MESO	DFS	Tertile	II,III,IV	0.686	0.370	.019	15	view →
READ	DFS	Tertile	All	0.689	0.379	.003	14	view →
COAD	OS	Tertile	IV	0.434	0.902	.001	12	view →
ESCA	OS	Tertile	IV	0.738	0.238	.024	12	view →
THCA	OS	Quartile	II,III,IV	1.000	0.342	.025	11	view →
SKCM	OS	Median	III,IV	0.937	0.741	.005	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

RPL5P6–UCEC (OS)

Open the UCEC breakdown →