RPL5P6

Across TCGA pan-cancer cohorts, RPL5P6 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of RPL5P6’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where RPL5P6 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL5P6 is over-expressed in tumor, although a few such as PAAD and UCEC show the opposite, repressed pattern.

LUAD, PAAD, and UCEC are the cancer types where RPL5P6 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL5P6 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	II,III,IV	+0.191	.006	4	view →
PAAD	Female	All	−0.295	.040	2	view →
UCEC	All	All	−0.149	.040	2	view →
BRCA	Female	II,III,IV	−0.039	.037	2	view →
KIRP	Female	All	−0.082	.044	1	view →
LIHC	All	II,III,IV	+0.055	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

RPL5P6–LUAD

Open the LUAD breakdown →