RPL5P16

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, RPL5P16 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RPL5P16’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RPL5P16 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL5P16 is over-expressed in tumor.

HNSC and BRCA are the cancer types where RPL5P16 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL5P16 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
HNSCMaleII,III,IV+0.020.0334view →
BRCAAllAll+0.062.0242view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

RPL5P16–HNSC

Tumor-vs-normal expression box plot for RPL5P16 RNA in HNSC.

Open the HNSC breakdown →

Exploration