RPL5

Across TCGA cell cohorts, RPL5 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. CNS shows the largest number of these associations.

The most reproducible RPL5-associated genes across cancer lineages are MMP26, FTMT, and AVPR1B. Each is linked with RPL5 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL5-to-partner and partner-to-RPL5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MMP26 grouped by RPL5-low versus RPL5-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL5→partner) and Y-score (partner→RPL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	MMP26 →	+0.026	+6.022	<.001	.001	3	2
SOFT_TISSUE	FTMT →	+0.086	+5.977	<.001	.001	3	1
SKIN	AVPR1B →	+0.013	+5.415	<.001	.004	3	1
CNS	PRSS54 →	+0.072	+5.754	<.001	.002	3	1
CNS	NPVF →	+0.172	+5.754	<.001	.002	3	1
CNS	DEFA4 →	+0.145	+5.754	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

MMP26 by RPL5 expression — SKIN

Explore this box plot interactively →