RPL4

Across TCGA cell cohorts, RPL4 mutation is significantly associated with the mutation status of many other genes, with 1,205 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RPL4-associated genes across cancer lineages are ZFPM1, NUCB1, and TACC3. Each is linked with RPL4 in more than 2 cancer types. Because this analysis shows association rather than direction, both RPL4-to-partner and partner-to-RPL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZFPM1 grouped by RPL4-low versus RPL4-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL4→partner) and Y-score (partner→RPL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	ZFPM1 →	+3.510	+4.108	.003	.003	1	3
BLOOD_Leukemia	NUCB1 →	+4.321	+5.285	.005	.005	1	3
LARGE_INTESTINE	TACC3 →	+3.350	+4.584	.003	.003	1	3
BREAST	YY1AP1 →	+4.857	+4.297	.009	.009	1	3
BLOOD_Lymphoma	LTBP4 →	+3.510	+4.108	.003	.003	1	3
BLOOD_Lymphoma	SIK3 →	+4.247	+4.554	.001	.001	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,205 associations by consensus.

ZFPM1 by RPL4 expression — BLOOD_Lymphoma

Explore this box plot interactively →