RPL39L

Across TCGA patient cohorts, RPL39L mutation is significantly associated with the RNA expression of many other genes, with 63 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL39L-associated genes across cancer lineages are MIR8076, LINC02439, and IQCF1. Each is linked with RPL39L in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL39L-to-partner and partner-to-RPL39L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR8076 grouped by RPL39L-low versus RPL39L-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL39L→partner) and Y-score (partner→RPL39L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR8076 →	+0.399	+5.436	<.001	.005	3	2
SKCM	LINC02439 →	+0.093	+6.797	<.001	<.001	3	2
UCEC	IQCF1 →	+0.302	+3.807	.007	.003	3	1
UCEC	METTL1P1 →	+0.262	+3.782	<.001	.005	3	1
UCEC	OR51A7 →	+0.155	+3.436	<.001	.003	3	1
UCEC	LINC02210-CRHR1 →	+0.102	+3.344	.003	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 63 associations by consensus.

MIR8076 by RPL39L expression — SKCM

Explore this box plot interactively →