RPL37AP8

Across TCGA pan-cancer cohorts, RPL37AP8 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated RPL37AP8 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher RPL37AP8 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RPL37AP8 expression acts as an unfavorable survival marker, although some lineages such as KIRP and GBM show a favorable association.

KIRP, UVM, and PAAD are the cancer types where RPL37AP8 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Tertile	All	0.928	0.388	<.001	52	view →
UVM	DFS	Quartile	All	0.433	0.826	<.001	36	view →
PAAD	DFS	Tertile	II,III,IV	0.345	0.562	.012	23	view →
BRCA	DFS	Tertile	All	0.427	0.576	<.001	20	view →
GBM	OS	Tertile	All	0.285	0.192	.019	18	view →
LGG	OS	Median	All	0.929	0.858	.002	18	view →
MESO	OS	Tertile	IV	0.758	0.326	.008	15	view →
SKCM	DFS	Tertile	II,III,IV	0.453	0.634	.004	13	view →
LUAD	DFS	Tertile	III,IV	0.906	0.559	.008	12	view →
KIRC	OS	Median	All	0.913	0.845	.015	11	view →
STAD	DFS	Median	II,III,IV	0.486	0.575	.027	8	view →
LIHC	DFS	Quartile	II,III,IV	0.258	0.500	.025	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

RPL37AP8–KIRP (DFS)

Open the KIRP breakdown →