RPL37AP8

Across TCGA pan-cancer cohorts, RPL37AP8 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of RPL37AP8’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RPL37AP8 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL37AP8 is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

COAD, THCA, and BRCA are the cancer types where RPL37AP8 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL37AP8 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	All	+2.497	<.001	7	view →
THCA	Male	All	−0.450	<.001	5	view →
BRCA	Female	All	−0.191	.002	4	view →
LUAD	All	All	+0.237	.006	3	view →
UCEC	All	IV	−1.780	.037	2	view →
READ	All	All	+0.767	.009	2	view →
KICH	All	All	−0.271	.013	2	view →
PRAD	All	All	+0.200	.016	2	view →
BLCA	Female	III,IV	+0.370	.040	1	view →
KIRC	Female	All	+0.215	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

RPL37AP8–COAD

Open the COAD breakdown →