RPL37A-DT

Across TCGA pan-cancer cohorts, RPL37A-DT RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of RPL37A-DT’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where RPL37A-DT RNA is repressed in tumor relative to normal tissue. In most cancer types RPL37A-DT is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, THCA, and HNSC are the cancer types where RPL37A-DT tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL37A-DT RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	IV	−1.510	<.001	11	view →
THCA	Male	All	−0.768	<.001	11	view →
HNSC	All	All	+0.177	.001	9	view →
LIHC	Male	II,III,IV	+0.679	<.001	8	view →
COAD	All	All	+0.201	<.001	8	view →
BLCA	All	All	+0.311	.006	6	view →
LUAD	Male	All	+0.480	.002	5	view →
CHOL	Male	All	+1.221	<.001	4	view →
STAD	All	All	+0.307	.004	4	view →
PRAD	All	All	+0.146	.049	2	view →
KIRP	All	II,III,IV	+0.473	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

RPL37A-DT–KICH

Open the KICH breakdown →