RPL35AP

Across TCGA pan-cancer cohorts, RPL35AP RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated RPL35AP data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RPL35AP RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPL35AP expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

KIRC, KICH, and UCS are the cancer types where RPL35AP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.720	0.825	.001	132	view →
KICH	DFS	Tertile	II,III,IV	0.043	0.950	<.001	78	view →
UCS	DFS	Tertile	IV	0.230	0.767	.009	36	view →
MESO	DFS	Tertile	All	0.137	0.510	.004	27	view →
GBM	OS	Tertile	All	0.317	0.435	.026	18	view →
READ	DFS	Tertile	IV	0.293	0.700	.003	18	view →
LUSC	DFS	Tertile	All	0.553	0.819	.001	12	view →
THCA	DFS	Tertile	IV	0.676	0.935	.044	9	view →
LIHC	OS	Tertile	III,IV	0.170	0.623	.001	9	view →
ESCA	DFS	Median	All	0.478	0.870	.030	4	view →
SKCM	OS	Tertile	All	0.927	0.861	.033	3	view →
COAD	OS	Tertile	II,III,IV	0.709	0.863	.027	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

RPL35AP–KIRC (OS)

Open the KIRC breakdown →