Across TCGA pan-cancer cohorts, RPL35AP RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of RPL35AP’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where RPL35AP RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL35AP is over-expressed in tumor.
LUAD are the cancer types where RPL35AP tumor–normal differential expression is most reproducible.