RPL34P22

Across TCGA patient cohorts, RPL34P22 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,923 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RPL34P22-associated GO terms across cancer lineages are Protein localization to vacuole, Regulation of organelle assembly, and Nuclear-transcribed mRNA catabolic process. Each is linked with RPL34P22 in more than 26 cancer types. Because this analysis shows association rather than direction, both RPL34P22-to-partner and partner-to-RPL34P22 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to vacuole grouped by RPL34P22-low versus RPL34P22-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL34P22→partner) and Y-score (partner→RPL34P22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Protein localization to vacuole →	+0.047	+0.503	.004	<.001	2	27
STAD	Regulation of organelle assembly →	+0.031	+0.266	<.001	<.001	3	26
THYM	Nuclear-transcribed mRNA catabolic process →	+0.045	+0.214	<.001	<.001	3	25
THYM	Autophagosome maturation →	+0.036	+0.175	<.001	<.001	3	25
STAD	Regulation of ubiquitin-dependent protein catabolic process →	+0.035	+0.253	<.001	<.001	3	25
LAML	Regulation of autophagosome assembly →	+0.046	+1.007	<.001	<.001	3	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,923 associations by consensus.

Protein localization to vacuole by RPL34P22 expression — ESCA

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