RPL34-DT

Across TCGA pan-cancer cohorts, RPL34-DT RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated RPL34-DT data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RPL34-DT RNA is associated with better overall survival. In most high-consensus cancer types, elevated RPL34-DT expression acts as an unfavorable survival marker, although some lineages such as KIRC and ESCA show a favorable association.

KIRC, ESCA, and UCEC are the cancer types where RPL34-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.742	0.533	<.001	73	view →
ESCA	DFS	Tertile	III,IV	0.619	0.243	.003	54	view →
UCEC	OS	Median	II,III,IV	0.753	0.404	.013	44	view →
ACC	DFS	Tertile	III,IV	0.535	0.073	.001	42	view →
UVM	OS	Tertile	All	0.960	0.778	.006	41	view →
KIRP	DFS	Quartile	All	0.955	0.825	.007	29	view →
HNSC	DFS	Tertile	IV	0.439	0.219	.001	27	view →
DLBC	DFS	Tertile	II,III,IV	1.000	0.650	.012	25	view →
UCS	OS	Tertile	II,III,IV	0.689	0.256	.005	22	view →
THYM	OS	Median	II,III,IV	0.960	0.680	.003	18	view →
CESC	DFS	Median	III,IV	0.188	0.591	.013	16	view →
LUAD	DFS	Tertile	IV	0.867	0.470	.023	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

RPL34-DT–KIRC (OS)

Open the KIRC breakdown →