RPL31P14

Across TCGA pan-cancer cohorts, RPL31P14 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of RPL31P14’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where RPL31P14 RNA is repressed in tumor relative to normal tissue. In most cancer types RPL31P14 is over-expressed in tumor, although a few such as THCA and KIRP show the opposite, repressed pattern.

THCA, KIRP, and LUAD are the cancer types where RPL31P14 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL31P14 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Female	II,III,IV	−0.637	<.001	9	view →
KIRP	All	All	−0.078	.001	5	view →
LUAD	Female	II,III,IV	−0.160	.007	2	view →
STAD	Male	All	−0.237	.044	1	view →
READ	Female	All	−0.178	.006	1	view →
LUSC	Female	II,III,IV	−0.160	.019	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

RPL31P14–THCA

Open the THCA breakdown →