RPL28

Across TCGA cell cohorts, RPL28 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,265 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RPL28-associated GO terms across cancer lineages are Regulation of protection from non-homologous end joining at telomere, Negative regulation of protection from non-homologous end joining at telomere, and Positive regulation of mRNA 3'-end processing. Each is linked with RPL28 in more than 7 cancer types. Because this analysis shows association rather than direction, both RPL28-to-partner and partner-to-RPL28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protection from non-homologous end joining at telomere grouped by RPL28-low versus RPL28-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL28→partner) and Y-score (partner→RPL28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of protection from non-homologous end joining at telomere →	+0.119	+0.519	.008	.004	3	8
STOMACH	Negative regulation of protection from non-homologous end joining at telomere →	+0.119	+0.519	.008	.004	3	8
OVARY	Positive regulation of mRNA 3'-end processing →	-0.106	-0.803	.004	<.001	3	8
STOMACH	Telomeric DNA-containing double minutes formation →	+0.119	+0.519	.008	.004	3	8
LARGE_INTESTINE	Positive regulation of protein acetylation →	-0.076	-0.537	<.001	<.001	3	8
BREAST	Protein targeting to lysosome →	-0.067	-0.927	.007	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,265 associations by consensus.

Regulation of protection from non-homologous end joining at telomere by RPL28 expression — STOMACH

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