RPL27A

Across TCGA cell cohorts, RPL27A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,755 significant associations in total. CNS shows the largest number of these associations.

The most reproducible RPL27A-associated GO terms across cancer lineages are Protein stabilization, Regulation of protein localization to nucleus, and Negative regulation of protein-containing complex assembly. Each is linked with RPL27A in more than 15 cancer types. Because this analysis shows association rather than direction, both RPL27A-to-partner and partner-to-RPL27A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein stabilization grouped by RPL27A-low versus RPL27A-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL27A→partner) and Y-score (partner→RPL27A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Protein stabilization →	-0.050	-0.658	.001	<.001	3	16
BONE	Regulation of protein localization to nucleus →	-0.074	-0.728	<.001	<.001	3	15
SOFT_TISSUE	Negative regulation of protein-containing complex assembly →	-0.073	-0.928	<.001	<.001	3	15
PANCREAS	Positive regulation of protein localization to nucleus →	-0.069	-0.811	<.001	<.001	3	14
CNS	Negative regulation of calcium ion export across plasma membrane →	-0.084	-0.999	<.001	<.001	3	14
OVARY	Schwann cell development →	-0.095	-0.736	<.001	.003	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,755 associations by consensus.

Protein stabilization by RPL27A expression — LARGE_INTESTINE

Explore this box plot interactively →