RPL27

Across TCGA cell cohorts, RPL27 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,941 significant associations in total. CNS shows the largest number of these associations.

The most reproducible RPL27-associated GO terms across cancer lineages are Regulation of intracellular protein transport, Vacuole organization, and Regulation of intracellular transport. Each is linked with RPL27 in more than 13 cancer types. Because this analysis shows association rather than direction, both RPL27-to-partner and partner-to-RPL27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of intracellular protein transport grouped by RPL27-low versus RPL27-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL27→partner) and Y-score (partner→RPL27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of intracellular protein transport →	-0.081	-0.719	<.001	.006	3	14
SOFT_TISSUE	Vacuole organization →	-0.042	-0.772	<.001	<.001	3	13
BONE	Regulation of intracellular transport →	-0.055	-0.549	.003	.005	3	12
SKIN	Lysosome organization →	-0.049	-0.418	<.001	<.001	3	12
SKIN	Lytic vacuole organization →	-0.049	-0.418	<.001	<.001	3	12
BONE	Protein localization to vacuole →	-0.069	-0.501	.003	<.001	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,941 associations by consensus.

Regulation of intracellular protein transport by RPL27 expression — UPPER_AERODIGESTIVE_TRACT

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